An updated meta-analysis to understand the variable efficacy of drotrecogin alfa (activated) in severe sepsis and septic shock

BACKGROUND: Significant debate continues over the efficacy of drotrecogin alpha activated (DAA) in sepsis. This updated meta-analysis provides an updated summary effect estimate and explores the reasons for outcome heterogeneity in placebo-controlled randomized clinical trials of DAA on 28-day all-c...

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Bibliographic Details
Main Authors: Lai, Peggy S., Matteau, Alexis, Iddriss, Adam, Hawes, Jennifer C.L., Ranieri, V. Marco, Thompson, B. Taylor
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725305/
https://ncbi.nlm.nih.gov/pubmed/23174922
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