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Why activated Protein C was not successful in severe sepsis and septic shock: Are we still tilting at windmills?
Drotrecogin alpha activated (DAA), trade name Xigris, is a recombinant human protein C that has been the subject of controversy since 2001 when it became the first biologic agent approved for the treatment of severe sepsis and septic shock. The PROWESS trial showed a 6.1% absolute reduction in 28-da...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3829688/ https://ncbi.nlm.nih.gov/pubmed/23925482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11908-013-0358-9 |
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