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Autophagy Gives a Nod and a Wink to the Inflammasome and Paneth Cells in Crohn’s Disease
Recent genome-wide association studies have linked polymorphisms in two atophagy genes, Atg16L1 and IRGM, with Crohn’s Disease. Now, experiments with Atg16L1 transgenic mice indicate multiple roles for autophagy in inflammatory bowel disease via effects on Paneth cells, a runaway inflammasome, and t...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725296/ https://ncbi.nlm.nih.gov/pubmed/19000829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.10.009 |
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