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Comparison of Selective versus Dual ET Receptor Antagonism on Cerebrovascular Dysfunction in Diabetes
OBJECTIVES: Cerebrovascular tone plays a key role in controlling cerebral blood flow. Our studies have demonstrated that the endothelin (ET) system is upregulated in type 2 diabetes leading to increased sensitivity to ET-1 and decreased relaxation in basilar artery (BA). While chronic ET(A) receptor...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725271/ https://ncbi.nlm.nih.gov/pubmed/21801593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/016164111X12881719352417 |
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