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Osteopontin expression is essential for interferon-α production by plasmacytoid dendritic cells
The observation that the T-bet transcription factor allows tissue-specific upregulation of intracellular osteopontin (Opn-i) in plasmacytoid dendritic cells (pDCs) suggests that Opn might contribute to the expression of interferon-α (IFN-α) in those cells. Here we show that Opn deficiency substantia...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725256/ https://ncbi.nlm.nih.gov/pubmed/16604075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1327 |
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