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Very long-term memories may be stored in the pattern of holes in the perineuronal net

A hypothesis and the experiments to test it propose that very long-term memories, such as fear conditioning, are stored as the pattern of holes in the perineuronal net (PNN), a specialized ECM that envelops mature neurons and restricts synapse formation. The 3D intertwining of PNN and synapses would...

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Detalhes bibliográficos
Autor principal: Tsien, Roger Y.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725115/
https://ncbi.nlm.nih.gov/pubmed/23832785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310158110
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