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Very long-term memories may be stored in the pattern of holes in the perineuronal net
A hypothesis and the experiments to test it propose that very long-term memories, such as fear conditioning, are stored as the pattern of holes in the perineuronal net (PNN), a specialized ECM that envelops mature neurons and restricts synapse formation. The 3D intertwining of PNN and synapses would...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2013
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725115/ https://ncbi.nlm.nih.gov/pubmed/23832785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310158110 |
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