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Deciphering the rules by which 5′-UTR sequences affect protein expression in yeast

The 5′-untranslated region (5′-UTR) of mRNAs contains elements that affect expression, yet the rules by which these regions exert their effect are poorly understood. Here, we studied the impact of 5′-UTR sequences on protein levels in yeast, by constructing a large-scale library of mutants that diff...

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Detalhes bibliográficos
Main Authors: Dvir, Shlomi, Velten, Lars, Sharon, Eilon, Zeevi, Danny, Carey, Lucas B., Weinberger, Adina, Segal, Eran
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725075/
https://ncbi.nlm.nih.gov/pubmed/23832786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222534110
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