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Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators

Transcription factors (TFs) are key mediators that propagate extracellular and intracellular signals through to changes in gene expression profiles. However, the rules by which promoters decode the amount of active TF into target gene expression are not well understood. To determine the mapping betw...

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Detalles Bibliográficos
Publicado en:Genome Res
Main Authors: van Dijk, David, Sharon, Eilon, Lotan-Pompan, Maya, Weinberger, Adina, Segal, Eran, Carey, Lucas B.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5204347/
https://ncbi.nlm.nih.gov/pubmed/27965290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.212316.116
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