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Modeling Pathogenesis of Huntington’s Disease with Inducible Neuroprogenitor Cells
Huntington’s disease (HD) is caused by an abnormal expansion of CAG trinucleotide repeats encoding polyglutamine (polyQ) in the first exon of the huntingtin (htt) gene. Despite considerable efforts, the pathogenesis of Huntington’s disease (HD) remains largely unclear due to a paucity of models that...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3724999/ https://ncbi.nlm.nih.gov/pubmed/21452052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-011-9679-0 |
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