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Mechanisms of resistance to sorafenib and the corresponding strategies in hepatocellular carcinoma

Sorafenib, the unique drug as first-line treatment for advanced hepatocellular carcinoma (HCC), has opened a window of hope after searching for effective agents to combat HCC for decades. However, the overall outcomes are far from satisfactory. One of the explanations is the genetic heterogeneity of...

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Bibliografske podrobnosti
Main Authors: Zhai, Bo, Sun, Xue-Ying
Format: Artigo
Jezik:Inglês
Izdano: Baishideng Publishing Group Co., Limited 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724962/
https://ncbi.nlm.nih.gov/pubmed/23898367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4254/wjh.v5.i7.345
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