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Myeloid-Derived Suppressor Cells Modulate Immune Responses Independently of NADPH Oxidase in the Ovarian Tumor Microenvironment in Mice

The phagocyte NADPH oxidase generates superoxide anion and downstream reactive oxidant intermediates in response to infectious threat, and is a critical mediator of antimicrobial host defense and inflammatory responses. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immat...

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Hlavní autoři: Godoy, Heidi E., Khan, A. Nazmul H., Vethanayagam, R. Robert, Grimm, Melissa J., Singel, Kelly L., Kolomeyevskaya, Nonna, Sexton, Kevin J., Parameswaran, Anupama, Abrams, Scott I., Odunsi, Kunle, Segal, Brahm H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724928/
https://ncbi.nlm.nih.gov/pubmed/23922763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069631
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