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Myeloid-Derived Suppressor Cells Modulate Immune Responses Independently of NADPH Oxidase in the Ovarian Tumor Microenvironment in Mice

The phagocyte NADPH oxidase generates superoxide anion and downstream reactive oxidant intermediates in response to infectious threat, and is a critical mediator of antimicrobial host defense and inflammatory responses. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immat...

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Detalhes bibliográficos
Main Authors: Godoy, Heidi E., Khan, A. Nazmul H., Vethanayagam, R. Robert, Grimm, Melissa J., Singel, Kelly L., Kolomeyevskaya, Nonna, Sexton, Kevin J., Parameswaran, Anupama, Abrams, Scott I., Odunsi, Kunle, Segal, Brahm H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724928/
https://ncbi.nlm.nih.gov/pubmed/23922763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069631
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