PEGylation of cationic, shell-crosslinked-knedel-like nanoparticles modulates inflammation and enhances cellular uptake in the lung

The airway provides a direct route for administration of nanoparticles bearing therapeutic or diagnostic payloads to the lung, however optimization of nanoplatforms for intracellular delivery remains challenging. Poly(ethylene glycol) (PEG) surface modification improves systemic performance but less...

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Main Authors: Ibricevic, Aida, Guntsen, Sean P., Zhang, Ke, Shrestha, Ritu, Liu, Yongjian, Sun, Jing Yi, Welch, Michael J., Wooley, Karen L., Brody, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724762/
https://ncbi.nlm.nih.gov/pubmed/23453959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2013.02.006
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