PEGylation of cationic, shell-crosslinked-knedel-like nanoparticles modulates inflammation and enhances cellular uptake in the lung

The airway provides a direct route for administration of nanoparticles bearing therapeutic or diagnostic payloads to the lung, however optimization of nanoplatforms for intracellular delivery remains challenging. Poly(ethylene glycol) (PEG) surface modification improves systemic performance but less...

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Main Authors: Ibricevic, Aida, Guntsen, Sean P., Zhang, Ke, Shrestha, Ritu, Liu, Yongjian, Sun, Jing Yi, Welch, Michael J., Wooley, Karen L., Brody, Steven L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724762/
https://ncbi.nlm.nih.gov/pubmed/23453959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2013.02.006
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