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Acetaldehyde-Derived Advanced Glycation End-Products Promote Alcoholic Liver Disease
BACKGROUND: Chronic ingestion of ethanol increases acetaldehyde and leads to the production of acetaldehyde-derived advanced glycation end-products (AA-AGE). We evaluated the toxicity of AA-AGE on hepatocytes and studied the role of AA-AGE in the pathogenesis of alcoholic liver disease (ALD). METHOD...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3724722/ https://ncbi.nlm.nih.gov/pubmed/23922897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070034 |
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