The Src Homology 3 Domain-containing Guanine Nucleotide Exchange Factor Is Overexpressed in High-grade Gliomas and Promotes Tumor Necrosis Factor-like Weak Inducer of Apoptosis-Fibroblast Growth Factor-inducible 14-induced Cell Migration and Invasion via Tumor Necrosis Factor Receptor-associated Factor 2

Glioblastoma (GB) is the highest grade of primary adult brain tumors, characterized by a poorly defined and highly invasive cell population. Importantly, these invading cells are attributed with having a decreased sensitivity to radiation and chemotherapy. TNF-like weak inducer of apoptosis (TWEAK)-...

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Detalhes bibliográficos
Main Authors: Fortin Ensign, Shannon P., Mathews, Ian T., Eschbacher, Jennifer M., Loftus, Joseph C., Symons, Marc H., Tran, Nhan L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724644/
https://ncbi.nlm.nih.gov/pubmed/23775076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.468686
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