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Rab Family Proteins Regulate the Endosomal Trafficking and Function of RGS4
RGS4, a heterotrimeric G-protein inhibitor, localizes to plasma membrane (PM) and endosomal compartments. Here, we examined Rab-mediated control of RGS4 internalization and recycling. Wild type and constitutively active Rab5 decreased RGS4 PM levels while increasing its endosomal targeting. Rab5, ho...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3724640/ https://ncbi.nlm.nih.gov/pubmed/23733193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.466888 |
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