A Novel Function of Onecut1 Protein as a Negative Regulator of MafA Gene Expression

The transcription factor MafA is a key regulator of insulin gene expression and maturation of islet β cells. Despite its importance, the regulatory mechanism of MafA gene expression is still unclear. To identify the transcriptional regulators of MafA, we examined various transcription factors, which...

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Hlavní autoři: Yamamoto, Kaoru, Matsuoka, Taka-aki, Kawashima, Satoshi, Takebe, Satomi, Kubo, Noriyo, Miyatsuka, Takeshi, Kaneto, Hideaki, Shimomura, Iichiro
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724624/
https://ncbi.nlm.nih.gov/pubmed/23775071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.481424
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