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Distinct Roles for Somatically and Dendritically Synthesized Brain-Derived Neurotrophic Factor in Morphogenesis of Dendritic Spines

Dendritic spines undergo the processes of formation, maturation, and pruning during development. Molecular mechanisms controlling spine maturation and pruning remain largely unknown. The gene for brain-derived neurotrophic factor (BDNF) produces two pools of mRNA, with either a short or long 3′ untr...

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Main Authors: Orefice, Lauren L., Waterhouse, Emily G., Partridge, John G., Lalchandani, Rupa R., Vicini, Stefano, Xu, Baoji
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724547/
https://ncbi.nlm.nih.gov/pubmed/23843530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0012-13.2013
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