RAF265 Inhibits the Growth of Advanced Human Melanoma Tumors

PURPOSE: The purpose of this preclinical study was to determine the effectiveness of RAF265, a multi-kinase inhibitor, for treatment of human metastatic melanoma and to characterize traits associated with drug response. EXPERIMENTAL DESIGN: Advanced metastatic melanoma tumors from 34 patients were o...

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Detalhes bibliográficos
Main Authors: Su, Yingjun, Vilgelm, Anna E., Kelley, Mark C., Hawkins, Oriana E., Liu, Yan, Boyd, Kelli L., Kantrow, Sara, Splittgerber, Ryan C., Short, Sarah P., Sobolik, Tammy, Zaja-Milatovic, Snjezana, Dahlman, Kimberly Brown, Amiri, Katayoun I., Jiang, Aixiang, Lu, Pengcheng, Shyr, Yu, Stuart, Darrin D., Levy, Shawn, Sosman, Jeffrey A., Richmond, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724517/
https://ncbi.nlm.nih.gov/pubmed/22351689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1122
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