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Programmed Cell Death 4 (PDCD4): A Novel Player in Ethanol Mediated Suppression of Protein Translation in Primary Cortical Neurons and Developing Cerebral Cortex

BACKGROUND: Prenatal exposure to ethanol elicits a range of neuro-developmental abnormalities, microcephaly to behavioral deficits. Impaired protein synthesis has been connected to pathogenesis of ethanol-induced brain damage and abnormal neuron development. However, mechanisms underlying these impa...

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Detalhes bibliográficos
Main Authors: Narasimhan, Madhusudhanan, Rathinam, Marylatha, Riar, Amanjot, Patel, Dhyanesh, Mummidi, Srinivas, Yang, Hsin-Shen, Colburn, Nancy H., Henderson, George I, Mahimainathan, Lenin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724449/
https://ncbi.nlm.nih.gov/pubmed/22757755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2012.01850.x
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