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Differential HIV epitope processing in monocytes and CD4 T cells affects cytotoxic T lymphocyte recognition
The ability of cytotoxic T lymphocytes (CTL) to clear virus-infected cells is dependent on the presentation of viral peptides processed intracellularly and displayed by MHC-I. Most CTL functional assays utilize exogenously added peptides, which does not account for kinetics and quantity of antigenic...
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Main Authors: | , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
2009
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3724235/ https://ncbi.nlm.nih.gov/pubmed/19505257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/599837 |
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