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Evidence for the involvement of G(i2) in activation of extracellular signal-regulated kinases in hepatocytes
BACKGROUND: Activation of the extracellular signal-regulated kinases ERK1 and ERK2 in hepatocytes by prostaglandin (PG)F(2α) was recently found to be inhibited by pertussis toxin (PTX) suggesting a role for G(i) proteins. RESULTS: Targeting the Gi(2α) expression by a specific ribozyme inhibited the...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC37242/ https://ncbi.nlm.nih.gov/pubmed/11495629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-2-13 |
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