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Searching for Synergies: Matrix Algebraic Approaches for Efficient Pair Screening

Functionally interacting perturbations, such as synergistic drugs pairs or synthetic lethal gene pairs, are of key interest in both pharmacology and functional genomics. However, to find such pairs by traditional screening methods is both time consuming and costly. We present a novel computational-e...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Gerlee, Philip, Schmidt, Linnéa, Monsefi, Naser, Kling, Teresia, Jörnsten, Rebecka, Nelander, Sven
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723843/
https://ncbi.nlm.nih.gov/pubmed/23935877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068598
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