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Searching for Synergies: Matrix Algebraic Approaches for Efficient Pair Screening

Functionally interacting perturbations, such as synergistic drugs pairs or synthetic lethal gene pairs, are of key interest in both pharmacology and functional genomics. However, to find such pairs by traditional screening methods is both time consuming and costly. We present a novel computational-e...

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Detalhes bibliográficos
Main Authors: Gerlee, Philip, Schmidt, Linnéa, Monsefi, Naser, Kling, Teresia, Jörnsten, Rebecka, Nelander, Sven
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723843/
https://ncbi.nlm.nih.gov/pubmed/23935877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068598
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