MiR-17 Partly Promotes Hematopoietic Cell Expansion through Augmenting HIF-1α in Osteoblasts

BACKGROUND: Hematopoietic stem cell (HSC) regulation is highly dependent on interactions with the marrow microenvironment, of which osteogenic cells play a crucial role. While evidence is accumulating for an important role of intrinsic miR-17 in regulating HSCs and HPCs, whether miR-17 signaling pat...

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Autores principales: Yang, Yuxia, Ma, Wei, Wu, Dan, Huang, Yu, Li, Hongge, Zou, Junhua, Zhang, Yanju, Feng, Meifu, Luo, Jianyuan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723828/
https://ncbi.nlm.nih.gov/pubmed/23936170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070232
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