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Kainate-induced calcium overload of cortical neurons in vitro: dependence on expression of AMPAR GluA2-subunit and down-regulation by subnanomolar ouabain

Whereas kainate (KA)-induced neurodegeneration has been intensively investigated, the contribution of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) in neuronal Ca(2+) overload ([Ca(2+)](i)) is still controversial. Using Ca2+ imaging and patch-clamp techniques, we found diff...

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Detalhes bibliográficos
Main Authors: Abushik, Polina A., Sibarov, Dmitry A., Eaton, Misty J., Skatchkov, Serguei N., Antonov, Sergei M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723740/
https://ncbi.nlm.nih.gov/pubmed/23721822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2013.05.002
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