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Kainate-induced calcium overload of cortical neurons in vitro: dependence on expression of AMPAR GluA2-subunit and down-regulation by subnanomolar ouabain
Whereas kainate (KA)-induced neurodegeneration has been intensively investigated, the contribution of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) in neuronal Ca(2+) overload ([Ca(2+)](i)) is still controversial. Using Ca2+ imaging and patch-clamp techniques, we found diff...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3723740/ https://ncbi.nlm.nih.gov/pubmed/23721822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2013.05.002 |
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