Regulation of the Tumor Suppressor PTEN through Exosomes: A Diagnostic Potential for Prostate Cancer

PTEN is a potent tumor-suppressor protein. Aggressive and metastatic prostate cancer (PC) is associated with a reduction or loss of PTEN expression. PTEN reduction often occurs without gene mutations, and its downregulation is not fully understood. Herein, we show that PTEN is incorporated in the ca...

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Detalhes bibliográficos
Main Authors: Gabriel, Kathleen, Ingram, Alistair, Austin, Richard, Kapoor, Anil, Tang, Damu, Majeed, Fadwa, Qureshi, Talha, Al-Nedawi, Khalid
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723640/
https://ncbi.nlm.nih.gov/pubmed/23936141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070047
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