Complement (C5-a)-induced granulocyte aggregation in vitro. A possible mechanism of complement-mediated leukostasis and leukopenia.

Activated plasma complement will induce biphasic aggregation of human granulocytes dectable by standard nephelometric techniques. The responsible active component was suggested to be C5a by molecular weight and heat-stability assays; moreover, aggragating activity was ablated by anti-C5 but not anti...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Craddock, P R, Hammerschmidt, D, White, J G, Dalmosso, A P, Jacob, H S
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1977
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372364/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/874088/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108763
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