Complement (C5-a)-induced granulocyte aggregation in vitro. A possible mechanism of complement-mediated leukostasis and leukopenia.

Activated plasma complement will induce biphasic aggregation of human granulocytes dectable by standard nephelometric techniques. The responsible active component was suggested to be C5a by molecular weight and heat-stability assays; moreover, aggragating activity was ablated by anti-C5 but not anti...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Craddock, P R, Hammerschmidt, D, White, J G, Dalmosso, A P, Jacob, H S
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1977
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372364/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/874088/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108763
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