Dietary Restriction Induced Longevity Is Mediated by Nuclear Receptor NHR-62 in Caenorhabditis elegans

Dietary restriction (DR) extends lifespan in a wide variety of species, yet the underlying mechanisms are not well understood. Here we show that the Caenorhabditis elegans HNF4α-related nuclear hormone receptor NHR-62 is required for metabolic and physiologic responses associated with DR-induced lon...

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Main Authors: Heestand, Bree N., Shen, Yidong, Liu, Wei, Magner, Daniel B., Storm, Nadia, Meharg, Caroline, Habermann, Bianca, Antebi, Adam
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723528/
https://ncbi.nlm.nih.gov/pubmed/23935515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003651
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