Neocosmospora sp-derived resorcylic acid lactones with in vitro binding affinity for human opioid and cannabinoid receptors

Bioassay-guided fractionation of a fungus Neocosmospora sp. (UM-031509) resulted in the isolation of three new resorcylic acid lactones, neocosmosin A (2), neocosmosin B (3) and neocosmosin C (4). Three known resorcylic acid lactones, monocillin IV (1), monocillin II (5) and radicicol (6) were also...

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Detalhes bibliográficos
Main Authors: Gao, Jiangtao, Radwan, Mohamed M., León, Francisco, Dale, Olivia Reed, Husni, Afeef S., Wu, Yunshan, Lupien, Shari, Wang, Xiaoning, Manly, Susan P., Hill, Robert A., Dugan, Frank M., Cutler, Horace G., Cutler, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723356/
https://ncbi.nlm.nih.gov/pubmed/23659286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np300653d
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