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Cripto/GRP78 modulation of the TGF-β pathway in development and oncogenesis
Cripto is a small, GPI-anchored signaling protein that regulates cellular survival, proliferation, differentiation and migration during normal developmental processes and tumorigenesis. Cripto functions as an obligatory co-receptor for the TGF-β ligands Nodal, GDF1 and GDF3 but attenuates signaling...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3723343/ https://ncbi.nlm.nih.gov/pubmed/22306319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.01.051 |
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