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Cripto/GRP78 modulation of the TGF-β pathway in development and oncogenesis

Cripto is a small, GPI-anchored signaling protein that regulates cellular survival, proliferation, differentiation and migration during normal developmental processes and tumorigenesis. Cripto functions as an obligatory co-receptor for the TGF-β ligands Nodal, GDF1 and GDF3 but attenuates signaling...

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Detalhes bibliográficos
Main Authors: Gray, Peter C., Vale, Wylie
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723343/
https://ncbi.nlm.nih.gov/pubmed/22306319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.01.051
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