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APRIL stimulates NF-κB-mediated HoxC4 induction for AID expression in mouse B cells

Activation-induced cytidine deaminase (AID) plays a key role in B cell immunoglobulin (Ig) class switch recombination (CSR) and somatic hypermutation (SHM). We have previously reported that the highly conserved homeodomain HoxC4 transcription factor binds to the Aicda (AID gene) promoter to induce A...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Park, Seok-Rae, Kim, Pyeung-Hyeun, Lee, Kyu-Seon, Lee, Sang-Hoon, Seo, Goo-Young, Yoo, Yung-Choon, Lee, Junglim, Casali, Paolo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723325/
https://ncbi.nlm.nih.gov/pubmed/23178148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2012.10.018
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