APRIL stimulates NF-κB-mediated HoxC4 induction for AID expression in mouse B cells

Activation-induced cytidine deaminase (AID) plays a key role in B cell immunoglobulin (Ig) class switch recombination (CSR) and somatic hypermutation (SHM). We have previously reported that the highly conserved homeodomain HoxC4 transcription factor binds to the Aicda (AID gene) promoter to induce A...

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Библиографические подробности
Главные авторы: Park, Seok-Rae, Kim, Pyeung-Hyeun, Lee, Kyu-Seon, Lee, Sang-Hoon, Seo, Goo-Young, Yoo, Yung-Choon, Lee, Junglim, Casali, Paolo
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723325/
https://ncbi.nlm.nih.gov/pubmed/23178148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2012.10.018
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