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ANTINOCICEPTIVE EFFECTS OF THE N-ACYLETHANOLAMINE ACID AMIDASE INHIBITOR ARN077 IN RODENT PAIN MODELS

Fatty acid ethanolamides (FAEs), which include palmitoylethanolamide (PEA) and oleoylethanolamide (OEA), are endogenous agonists of peroxisome proliferator-activated receptor-α (PPAR-α) and important regulators of the inflammatory response. They are degraded in macrophages by the lysosomal cysteine...

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Main Authors: Sasso, Oscar, Moreno-Sanz, Guillermo, Martucci, Cataldo, Realini, Natalia, Dionisi, Mauro, Mengatto, Luisa, Duranti, Andrea, Tarozzo, Glauco, Tarzia, Giorgio, Mor, Marco, Bertorelli, Rosalia, Reggiani, Angelo, Piomelli, Daniele
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723234/
https://ncbi.nlm.nih.gov/pubmed/23218523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2012.10.018
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