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Integrative Analysis of Methylome and Transcriptome Reveals the Importance of Unmethylated CpGs in Non-CpG Island Gene Activation

Background. Promoter methylation is associated with gene repression; however, little is known about its mechanism. It was proposed that the repression of methylated genes is achieved through the recruitment of methyl binding proteins (MBPs) that participate in closing the chromatin. An alternative m...

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Main Authors: Marx, Amichai, Kahan, Tamar, Simon, Itamar
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722964/
https://ncbi.nlm.nih.gov/pubmed/23936848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/785731
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