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The 5'-end transitional CpGs between the CpG islands and retroelements are hypomethylated in association with loss of heterozygosity in gastric cancers

BACKGROUND: A loss of heterozygosity (LOH) represents a unilateral chromosomal loss that reduces the dose of highly repetitive Alu, L1, and LTR retroelements. The aim of this study was to determine if the LOH events can affect the spread of retroelement methylation in the 5'-end transitional ar...

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Detalhes bibliográficos
Main Authors: Kim, Young-Ho, Hong, Seung-Jin, Jung, Yu-Chae, Kim, Sung-Ja, Seo, Eun-Joo, Choi, Sang-Wook, Rhyu, Mun-Gan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1552088/
https://ncbi.nlm.nih.gov/pubmed/16827945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-180
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