The 5'-end transitional CpGs between the CpG islands and retroelements are hypomethylated in association with loss of heterozygosity in gastric cancers

BACKGROUND: A loss of heterozygosity (LOH) represents a unilateral chromosomal loss that reduces the dose of highly repetitive Alu, L1, and LTR retroelements. The aim of this study was to determine if the LOH events can affect the spread of retroelement methylation in the 5'-end transitional ar...

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Hlavní autoři: Kim, Young-Ho, Hong, Seung-Jin, Jung, Yu-Chae, Kim, Sung-Ja, Seo, Eun-Joo, Choi, Sang-Wook, Rhyu, Mun-Gan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2006
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1552088/
https://ncbi.nlm.nih.gov/pubmed/16827945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-180
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