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Analysis of the effects of rare variants on splicing identifies alterations in GABA(A) receptor genes in autism spectrum disorder individuals

A large-scale sequencing screen of X-linked synaptic genes in individuals with autism spectrum disorder (ASD) or schizophrenia (SCZ), two common neurodevelopmental disorders, identified many variants most of which have no easily predictable effect on gene function. In this report, we evaluated the i...

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Detalhes bibliográficos
Main Authors: Piton, Amélie, Jouan, Loubna, Rochefort, Daniel, Dobrzeniecka, Sylvia, Lachapelle, Karine, Dion, Patrick A, Gauthier, Julie, Rouleau, Guy A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722945/
https://ncbi.nlm.nih.gov/pubmed/23169495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.243
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