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Phenotypic variant of Brachydactyly-mental retardation syndrome in a family with an inherited interstitial 2q37.3 microdeletion including HDAC4

Deletions of the chromosomal region 2q37 cause brachydactyly-mental retardation syndrome (BDMR), also known as Albright hereditary osteodystrophy-like syndrome. Recently, histone deacetylase 4 (HDAC4) haploinsufficiency has been postulated to be the critical genetic mechanism responsible for the mai...

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Библиографические подробности
Главные авторы: Villavicencio-Lorini, Pablo, Klopocki, Eva, Trimborn, Marc, Koll, Randi, Mundlos, Stefan, Horn, Denise
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722943/
https://ncbi.nlm.nih.gov/pubmed/23188045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.240
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