Mesenchymal stem cells (MSCs) from scleroderma patients (SSc) preserve their immunomodulatory properties although senescent and normally induce T regulatory cells (T(regs)) with a functional phenotype: implications for cellular-based therapy

Systemic sclerosis (SSc) is a chronic disease, with early activation of the immune system. The aim of our work was to address how SSc–mesenchymal stem cells (MSCs), although senescent, might preserve specific immunomodulatory abilities during SSc. MSCs were obtained from 10 SSc patients and 10 healt...

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Detalhes bibliográficos
Main Authors: Cipriani, P, Di Benedetto, P, Liakouli, V, Del Papa, B, Di Padova, M, Di Ianni, M, Marrelli, A, Alesse, E, Giacomelli, R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722920/
https://ncbi.nlm.nih.gov/pubmed/23607751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12111
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