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Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ

Protein N-myristoylation is a 14-carbon fatty-acid modification that is conserved across eukaryotic species and occurs on nearly 1% of the cellular proteome(1,2). The ability of the myristoyl group to facilitate dynamic protein–protein and protein–membrane interactions (known as the myristoyl switch...

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Detalhes bibliográficos
Main Authors: Burnaevskiy, Nikolay, Fox, Thomas G., Plymire, Daniel A., Ertelt, James M., Weigele, Bethany A., Selyunin, Andrey S., Way, Sing Sing, Patrie, Steven M., Alto, Neal M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722872/
https://ncbi.nlm.nih.gov/pubmed/23535599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12004
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