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Intrarenal dynamics in the pathogenesis and prevention of acute urate nephropathy.

Tubular fluid flow, urine osmolality, and pH were selectively altered to determine the relative protective roles of these factors in a rat model of acute urate nephrophathy. Various prehyper uricemic conditions were established in five groups of animals: (a) normopenic Wistar rats given no pretreatm...

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Pubblicato in:J Clin Invest
Autori principali: Conger, J D, Falk, S A
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1977
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372286/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16037/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108700
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