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Evaluation of PPP2R2A as a prostate cancer susceptibility gene: comprehensive germline and somatic study

PPP2R2A, mapped to 8p21.2, encodes for the α isoform of the regulatory B55 subfamily of the protein phosphatase 2 (PP2A). PP2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Because of its known functions and location within a chr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cheng, Yu, Liu, Wennuan, Kim, Seong-Tae, Sun, Jishan, Lu, Lingyi, Sun, Jielin, Zheng, Siqun Lilly, Isaacs, William B., Xu, Jianfeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722858/
https://ncbi.nlm.nih.gov/pubmed/21872824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergen.2011.05.002
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