Abnormal XPD-induced nuclear receptor transactivation in DNA repair disorders: trichothiodystrophy and xeroderma pigmentosum

XPD (ERCC2) is a DNA helicase involved in nucleotide excision repair and in transcription as a structural bridge tying the transcription factor IIH (TFIIH) core with the cdk-activating kinase complex, which phosphorylates nuclear receptors. Mutations in XPD are associated with several different phen...

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Bibliografiset tiedot
Päätekijät: Zhou, Xiaolong, Khan, Sikandar G, Tamura, Deborah, Ueda, Takahiro, Boyle, Jennifer, Compe, Emmanuel, Egly, Jean-Marc, DiGiovanna, John J, Kraemer, Kenneth H
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2013
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722669/
https://ncbi.nlm.nih.gov/pubmed/23232694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.246
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