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CD47 gene knockout protects against transient focal cerebral ischemia in mice

CD47 is a cell surface glycoprotein that helps mediate neutrophil transmigration across blood vessels. The present study was performed to determine whether absence of the CD47 gene decreases focal ischemic brain damage. Mice were subjected to 90 minutes middle cerebral artery occlusion. CD47 knockou...

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Hlavní autoři: Jin, Guang, Tsuji, Kiyoshi, Xing, Changhong, Yang, Yongguang, Wang, Xiaoying, Lo, Eng H
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722607/
https://ncbi.nlm.nih.gov/pubmed/19233173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.02.004
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