CD47 gene knockout protects against transient focal cerebral ischemia in mice

CD47 is a cell surface glycoprotein that helps mediate neutrophil transmigration across blood vessels. The present study was performed to determine whether absence of the CD47 gene decreases focal ischemic brain damage. Mice were subjected to 90 minutes middle cerebral artery occlusion. CD47 knockou...

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Bibliographic Details
Main Authors: Jin, Guang, Tsuji, Kiyoshi, Xing, Changhong, Yang, Yongguang, Wang, Xiaoying, Lo, Eng H
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722607/
https://ncbi.nlm.nih.gov/pubmed/19233173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.02.004
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