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Stage Specific Requirement of Gfrα1 in the Ureteric Epithelium during Kidney Development

Glial cell line-derived neurotrophic factor (GDNF) binds a coreceptor GDNF family receptor α1 (GFRα1) and forms a signaling complex with the receptor tyrosine kinase RET. GDNF-GFRα1-RET signaling activates cellular pathways that are required for normal induction of the ureteric bud (UB) from the Wol...

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Autori principali: Davis, T. Keefe, Hoshi, Masato, Jain, Sanjay
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722262/
https://ncbi.nlm.nih.gov/pubmed/23542432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2013.03.001
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