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Difluorinated-Curcumin (CDF) Restores PTEN Expression in Colon Cancer Cells by Down-Regulating miR-21

Despite recent advancement in medicine, nearly 50% of patients with colorectal cancer show recurrence of the disease. Although the reasons for the high relapse are not fully understood, the presence of chemo- and radiotherapy-resistant cancer stem/stem-like cells, where many oncomirs like microRNA-2...

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Main Authors: Roy, Sanchita, Yu, Yingjie, Padhye, Subhash B., Sarkar, Fazlul H., Majumdar, Adhip P.N.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722247/
https://ncbi.nlm.nih.gov/pubmed/23894315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068543
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