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Evaluation of multi-well microelectrode arrays for neurotoxicity screening using a chemical training set

Microelectrode array (MEA) approaches have been proposed as a tool for detecting functional changes in electrically excitable cells, including neurons, exposed to drugs, chemicals or particles. However, conventional single well-MEA systems lack the throughput necessary for screening large numbers of...

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Detalhes bibliográficos
Main Authors: McConnell, Emma R., McClain, Maxine A., Ross, James, LeFew, William R., Shafer, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721981/
https://ncbi.nlm.nih.gov/pubmed/22652317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2012.05.001
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