A secreted bacterial protease tailors the Staphylococcus aureus virulence repertoire to modulate bone remodeling during osteomyelitis

Osteomyelitis is a common manifestation of invasive Staphylococcus aureus infection. Pathogen-induced bone destruction limits antimicrobial penetration to the infectious focus and compromises treatment of osteomyelitis. To investigate mechanisms of S. aureus-induced bone destruction, we developed a...

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Bibliographic Details
Main Authors: Cassat, James E., Hammer, Neal D., Campbell, J. Preston, Benson, Meredith A., Perrien, Daniel S., Mrak, Lara N., Smeltzer, Mark S., Torres, Victor J., Skaar, Eric P.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721972/
https://ncbi.nlm.nih.gov/pubmed/23768499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.05.003
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