Repurposing the Nonsteroidal Anti-inflammatory Drug Diflunisal as an Osteoprotective, Antivirulence Therapy for Staphylococcus aureus Osteomyelitis

Staphylococcus aureus osteomyelitis is a common and debilitating invasive infection of bone. Treatment of osteomyelitis is confounded by widespread antimicrobial resistance and the propensity of bacteria to trigger pathological changes in bone remodeling that limit antimicrobial penetration to the i...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Hendrix, Andrew S., Spoonmore, Thomas J., Wilde, Aimee D., Putnam, Nicole E., Hammer, Neal D., Snyder, Daniel J., Guelcher, Scott A., Skaar, Eric P., Cassat, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997817/
https://ncbi.nlm.nih.gov/pubmed/27324764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00834-16
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